NTI Complete In Vitro Studies on Cannabis Strains, Clinical Trials Await

Published at Dec 21, 2020, in ASX Biotechs

Neurotech International Ltd (ASX:NTI) has today confirmed the successful completion of in-vitro studies using human brain cells to assess and validate the anti-inflammatory and neuro-modulatory properties of its proprietary DOLCE/NTI cannabis leads.

In vitro studies are those done in the laboratory within the confines of a test tube or laboratory dish. Neurotech’s in vitro studies have shown the superiority of the DOLCE/NTI strains over CBD alone and now pave the way for future studies, including phase 1 clinical trials.

Neurotech has been undertaking a series of in-vitro studies to assess the neuroprotective, anti-inflammatory and neuro-modulatory activities of the proprietary DOLCE/NTI cannabis leads CBDA, CBDP, CBDB.

The DOLCE/NTI strains are unique in that they contain minimal THC (<0.3%), which may result in a less onerous regulatory pathway to commercialisation (any cannabis strain with a THC level above 0.3% is regulated as a narcotic).

The in-vitro studies were conducted at three leading independent laboratories – Monash University, University of Wollongong and RMIT University.

Neurotech previously reported the mode of action and powerful neuro-protective and modulatory properties of these unique strains versus CBD alone. These in vitro findings have been further validated in these final trials.

As many as one billion people suffer from a neurological disorder

DOLCE/NTI strains have shown to significantly improve neuronal cell health, cell viability and have the potent ability to reduce inflammation compared with CBD alone.

All these physiological processes are vital in managing disorders with unmet need for therapies including; Autism, Epilepsy, ADHD, Alzheimer’s disease and related neurological disorders.

The World Health Organisation estimated that in 2006, as many as ‘one billion people’ suffered from a neurological disorder. Without effective treatments or cures, the number of those affected by neurological disorders will continue to increase as the world’s population grows.

With a range of disorders impacting so many people, the market opportunity for Neurotech is large. The global market size is estimated to be $112BN per year by 2027, growing at a rate of 5% per annum.

Path cleared for Phase 1 clinical trials

Neurotech’s in vitro studies have shown the superiority of the DOLCE/NTI strains over CBD alone and now pave the way for future studies, including phase 1 clinical trials.

Phase 1 clinical study preparations are currently underway to develop the optimum delivery and dosage forms.

Commencement of stage 1 is expected in Q1/ 2021. Clinical trials will be conducted under the guidance and supervision of A/Professor Michael Fahey (Head of Paediatric Neurology, Monash Children's Hospital).

A/Professor Fahey recently completed his prestigious Fulbright scholarship in the USA and has extensive experience in the clinical development and management of medicinal cannabis in children with autism and related neurological disorders.

A/Prof Fahey and his team are experts in neurodevelopment and neuroprotection studies across various patient groups. "Preclinical studies suggest that these strains exhibit potent and unique properties when compared to CBD alone and warrant the further assessment of these strains in phase 1 clinical trials," said A/Prof Fahey.

“These final trial results are very encouraging, in particular, the powerful anti-inflammatory mode of action of our strains compared to CBD alone,” said Brian Leedman, Chairman of Neurotech. These results demonstrate that the DOLCE/NTI leads may have a broader application in relation to the management and treatment of a number of neurological disorders”.

Neurotech continues to progress the development of its propriety cannabis strains, and is setting itself up for an active first half in 2021.

Where to invest $1,000 right now

S3 Consortium Pty Ltd (CAR No.433913) is a corporate authorised representative of LeMessurier Securities Pty Ltd (AFSL No. 296877). The information contained in this article is general information only. Any advice is general advice only. Neither your personal objectives, financial situation nor needs have been taken into consideration. Accordingly you should consider how appropriate the advice (if any) is to those objectives, financial situation and needs, before acting on the advice.

Conflict of Interest Notice

S3 Consortium Pty Ltd does and seeks to do business with companies featured in its articles. As a result, investors should be aware that the Firm may have a conflict of interest that could affect the objectivity of this article. Investors should consider this article as only a single factor in making any investment decision. The publishers of this article also wish to disclose that they may hold this stock in their portfolios and that any decision to purchase this stock should be done so after the purchaser has made their own inquires as to the validity of any information in this article.

Publishers Notice

The information contained in this article is current at the finalised date. The information contained in this article is based on sources reasonably considered to be reliable by S3 Consortium Pty Ltd, and available in the public domain. No “insider information” is ever sourced, disclosed or used by S3 Consortium.

Australian ASX Small Cap stocks | Why Finfeed.com is Australia’s leading small cap publication

Founded seven years ago, Finfeed.com is Australia’s leading and longest standing website for investor and finance news, education and expert opinion.

Published by StocksDigital, Finfeed was created to report daily on the comings and goings of ASX listed stocks in the small cap market.

As the first digital publication dedicated specifically to this space, Finfeed soon became the most trusted publication in the market, quickly garnering over two million page views – a number that continues to rise.

Finfeed.com provides its readers with informative articles that tackle the latest in market moving #ASX small cap news, plus exclusive content you won’t find anywhere else. It is aimed at those with an interest in investing, market education, company performance, start-ups and much more.

Finfeed.com is the only media organisation operating under the strength of a Financial Services License and is backed by leading journalists and analysts all with brands of their own.

The website aims to inform, educate and entertain with content that drills down into the heart of financial matters.

Finfeed is a leading source of investor and market information, with everything investors need to know about how to invest written in a way that anyone can understand. 

Over the years, the website has expanded beyond exclusively reporting on small caps, to profile Australia’s leading ASX listed small, mid and large caps as well as some of the country’s most successful CEOs and business leaders to find out what makes them tick.

Every day you will find fresh content covering:

Fast Facts

Over 4,000 articles published

Over 2.3 Million Page Views and counting

Over 10,000 followers on social media

Subscriber list growing by 2% monthly

Thanks for subscribing!