Dimerix Chief Scientist awarded Novartis Prize

Published at Jun 15, 2016, in ASX Biotechs

The Chief Scientific Advisor at Dimerix (ASX:DXB), an Australian biotechnology company developing technology for better diagnoses and treatment of chronic kidney disease (CKD), has been awarded the Novartis Prize by the British Pharmacological Society.

The award was given to Professor Kevin Pfleger for his “pioneering research, including the discovery of Dimerix’s lead development program, DMX-200”, currently undergoing clinical trials.

Professor Kevin Pfleger, Chief Scientific Advisor at Dimerix

DMX-200 combines irbesartan and propagermanium in the treatment of chronic kidney disease (CKD) and has been shown to improve the outcome of CKD by reducing proteinuria by more than 50% in animal tests.

Professor Pfleger is also the co-inventor of the Receptor-HIT technology assigned to Dimerix from The University of Western Australia. Receptor-HIT was used to identify the DMX-200 therapy in an internal drug development program, initially for the treatment of a subset of patients with chronic kidney disease. DXB is pursuing a treatment for CKD through the application of the DMX-200 therapy which is expected to serve as DXB’s flagship treatment. In addition to its own therapeutic programs, DXB also earns revenue by providing Receptor-HIT to third party pharmaceutical firms around the world.

In response to the news, DXB Executive Chairman Dr. James Williams hopes the award will serve as a validator for the development work being done by DXB, and says that, “It is great news that Kevin’s work has been recognised in this way by the British Pharmacological Society, and we congratulate Kevin on this achievement. The multiple drug programs we are now able to commercialise based on his world-leading research offer great hope to a large number of people worldwide.”

Finfeed interviewed Mr. Williams in late March 2016, discussing DXB’s kidney disease research, its recent progress as well as future plans.

Professor Pfleger has also won other prestigious awards in recent years, within biochemistry. He was named Western Australian Young Scientist of the Year 2009 and his work featured as one of the NHMRC 10 of the Best Research Projects 2010. In 2011, he was awarded the Australian Museum Eureka Prize for Emerging Leader in Science, in 2012 he won The Endocrine Society Early Investigators Award and the WA Young Tall Poppy Science Award.

Professor Pfleger will receive the Novartis prize and the US$3,000 winners prize, as part of the British Pharmacological Society’s annual meeting, held every December in London, UK.

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